Plumbagin (5-Hydroxy-2-methyl-1,4-naphthoquinone) is a plant-derived naphthoquinone possessing a number of pharmacological activities. A yellow pigment. It has been shown to have antimicrobial activity. In animals, it has antimalarial, anticarcinogenic, cardiotonic, antifertilityaction, and anti-atherosclerosis effects.

Plumbagin is named after the plant genus Plumbago, from which it was originally isolated.

Regarded as a toxin.


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