• Principle of Least Astonishment, a concept in the study of human-computer interaction
• Participatory Learning and Action, an approach used in international development
• People's Liberation Army of the People's Republic of China
• Palestinian Liberation Army
• An early name of the Irish National Liberation Army
• Phone Losers of America, the computer and telephone hacking group
• Port of London Authority
• Prior Learning Assessment in the field of education and articulation.
• Pre-school learning alliance, a charitable organisation formed by a number of playschools/groups in the UK
• Programmable logic array, a programmable device used to implement combinational logic circuits
• Product licensing application, an application to the Food and Drug Administration to get approval of a biologic product
• Public Library Association, a division of the American Library Association
• Punjab Library Association, an association in the Indian Punjab, first founded in 1916 at Lahore by Asa Don Dickinson.
• Polylactic acid, a biopolymer made from natural sugar sources, which can be used as a substitute for petroleum-based polymers
• Protected Landscape Area, a type of protected areas in Slovakia and the Czech Republic

Other meanings

• The Playboy Enterprises stock symbol
• The ProLife Alliance, a minor political party in the United Kingdom