Perseverance is a term for human endurance and autonomy which may refer to:

• Perseverance (album), an album by metalcore band Hatebreed
• Perseverance (Percee P album), an album by rapper Percee P
• Perseverance (steam locomotive), a 19th century steam locomotive
• Perseverance (solitaire), a card game
• Perseverance of the saints, a doctrine of some Christian churches
• 975 Perseverantia, a minor planet in the Solar System
• Perseverance (friendship), A relation that never tires out till the end of world. Perseverance is the affinity towards creating friendship out of thin air