Palisade is a Statutory Town in Mesa County, Colorado, United States. It is part of the Grand Junction Metropolitan Statistical Area. The population was 2,579 at the 2000 census.
Palisade is known for its peach orchards and wine vineyards, and is Colorado's peach capitol.
According to the United States Census Bureau, the town has a total area of 1.1 square miles (2.8 km²), of which, 1.1 square miles (2.8 km²) of it is land and 0.92% is water.
There were 1,051 households out of which 30.5% had children under the age of 18 living with them, 49.8% were married couples living together, 12.0% had a female householder with no husband present, and 34.4% were non-families. 29.5% of all households were made up of individuals and 12.9% had someone living alone who was 65 years of age or older. The average household size was 2.35 and the average family size was 2.91.
In the town the population was spread out with 24.3% under the age of 18, 7.6% from 18 to 24, 26.5% from 25 to 44, 21.5% from 45 to 64, and 20.2% who were 65 years of age or older. The median age was 40 years. For every 100 females there were 87.8 males. For every 100 females age 18 and over, there were 85.3 males.
The median income for a household in the town was $27,739, and the median income for a family was $31,797. Males had a median income of $28,231 versus $21,875 for females. The per capita income for the town was $15,539. About 11.0% of families and 14.0% of the population were below the poverty line, including 21.2% of those under age 18 and 10.7% of those age 65 or over.