EPOC is accompanied by an elevated consumption of fuel, and while some studies found that included an elevated consumption of fat, others did not find a similar effect. None of the studies set up to investigate the effect used very large sample sizes, possibly due to the cost of conducting the experiments.
, but the difference is partly offset by the higher increase in caloric expenditure that occurs during the EPOC phase after anaerobic exercise. Anaerobic exercise in the form of high-intensity interval training was also found in one study to result in greater loss of subcutaneous fat, even though the subjects expended fewer than half as many calories during exercise.
Whether this result was caused by the EPOC effect has not been established, and the caloric content of the participants' diet was not controlled during this particular study period.In their 2004 survey of the relevant literature, Meirelles and Gomes found: "In summary, EPOC resulting from a single resistance exercise session does not represent a great impact on energy balance; however, its cumulative effect may be relevant.". This is echoed by Reynolds and Kravitz in their survey of the literature where they remarked: "However, it should be emphasized that the overall weight-control benefits of EPOC, for men and women, from participation in resistance exercise occur over a significant time period, since kilocalories are expended at a low rate in the individual postexercise sessions.
What is clear is that the EPOC effect is greater the greater the intensity of the exercise and the greater the time spent during the exercise phase. Most studies found a linear relationship with time of exercise and the effect. One found a curvilinear relationship between the intensity and the EPOC effect, though others found a linear relationship.