If the points are (x,y) and (u,v), then they are hyperbolically orthogonal if
If two hyperbolically-orthogonal points form two angles with the horizontal axis, then they are complementary angles.
Since Hermann Minkowski's foundation for spacetime study in 1908, the concept of points in a spacetime plane being hyperbolic-orthogonal to a timeline (tangent to a World line) has been used to define simultaneity of events relative to the timeline. To see Minkowski's use of the concept, click on the link below and scroll down to the expression
To get away from the dependence on analytic geometry in the above definition, Edwin Bidwell Wilson and Gilbert N. Lewis provided an approach using the ideas of synthetic geometry in 1912: the radius to a point on an hyperbola and the tangent line at that point are hyperbolic-orthogonal. They note (p.415) "in our plane no pair of perpendicular [hyperbolic-orthogonal] lines is better suited to serve as coordinate axes than any other pair", an expression of the Principle of relativity.