, a gentamicin 2"-nucleotidyltransferase
is an enzyme
the chemical reaction
- nucleoside triphosphate + gentamicin diphosphate + 2"-nucleotidylgentamicin
Thus, the two substrates of this enzyme are nucleoside triphosphate and gentamicin, whereas its two products are diphosphate and 2-nucleotidylgentamicin.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is NTP:gentamicin 2"-nucleotidyltransferase. Other names in common use include gentamicin 2"-adenylyltransferase, aminoglycoside adenylyltransferase, and gentamicin 2"-nucleotidyltransferase.
- Angelatou F, Litsas SB, Kontomichalou P "Purification and properties of two gentamicin-modifying enzymes, coded by a single plasmid pPK237 originating from Pseudomonas aeruginosa". J. Antibiot. 235–44.
- Naganawa H, Yagisawa M, Kondo S, Takeuchi T, Umezawa H "The structure determination of an enzymatic inactivation product of 3',4'-dideoxykanamycin B". J. Antibiot. 913–4.
- Yagisawa M, Naganawa H, Kondo S, Hamada M, Takeuchi T "Adenylyldideoxykanamycin B, a product of the inactivation of dideoxykanamycin B by Escherichia coli carrying R factor". J. Antibiot. 911–2.
- The CAS registry number for this enzyme class is .
Gene Ontology (GO) codes