Myositis ossificans comprises two syndromes characterized by heterotopic ossification (calcification) of muscle.
The condition rarely is asymptomatic, and may sometimes be diagnosed from radiographs obtained for unrelated problems.
Most (i.e. 80%) ossifications arise in the thigh or arm, and are caused by a premature return to activity after an injury. Other sites include intercostal spaces, erector spinae, pectoralis muscles, glutei, and the chest. Hazy densities are sometimes noted approximately one month after injury, while the denser opacities eventually seen may not be apparent until two months have passed
Treatment is initially conservative, as some patients' calcifications will spontaneously be reabsorbed, and others will have minimal symptoms. In occasional cases, surgical debridement of the abnormal tissue is required, although success of such therapy is limited.
Jumbo gene offers clue to Parkinson's. (researchers discover massive gene dubbed 'parkin' that may reveal what triggers neuronal death caused by disease)
Apr 10, 1998; People with Parkinson's disease often can't keep their hands from trembling or relax their face to form a smile. For years...