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Nitrosourea
Nitrosourea is both the name of a molecule, and a class of compounds that include a nitroso (R-NO) group and a urea.
Examples include:
Nitrosourea compounds are DNA alkylating agents and are often used in chemotherapy. They are lipophilic and thus can cross the blood-brain barrier, making them useful in the treatment of brain tumors such as glioblastoma multiforme.
Side Effects
Some nitrosoureas (e.g. Lomustine) have been associated with the development of interstitial lung diseaseExternal links
References
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This article is licensed under the GNU Free Documentation License.
Last updated on Saturday June 07, 2008 at 13:32:06 PDT (GMT -0700)
View this article at Wikipedia.org - Edit this article at Wikipedia.org - Donate to the Wikimedia Foundation
This article is licensed under the GNU Free Documentation License.
Last updated on Saturday June 07, 2008 at 13:32:06 PDT (GMT -0700)
View this article at Wikipedia.org - Edit this article at Wikipedia.org - Donate to the Wikimedia Foundation
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