Nitrosourea is both the name of a molecule, and a class of compounds that include a nitroso (R-NO) group and a urea.
Nitrosourea compounds are DNA alkylating agents and are often used in chemotherapy. They are lipophilic and thus can cross the blood-brain barrier, making them useful in the treatment of brain tumors such as glioblastoma multiforme.
Some nitrosoureas (e.g. Lomustine) have been associated with the development of interstitial lung disease