, in its original and most general sense, refers to any swelling of a nerve. (Neuro-
is from the Greek for nerve
, where as the suffix -oma
.) Just as the Latin word for swelling (tumor
) is now restricted to neoplasias
, the equivalent Greek suffix -oma
has shared in that fate. Thus, the typical modern usage of neuroma
is for nerve tumors. However, many of the older, more general uses still persist.
Neoplastic neuromas are tumors of nerves, although the term can also be applied more generally for a tumor of nervous system tissue. They can be derived from a variety of the cell types that constitute nervous tissue, including glial cells and neurons, and can be either benign or malignant (i.e. cancerous). Many mistakenly assume that the Greek stem neur in neuroma refers to neurons rather than to nerves. This is not the case, and in fact, most instances of the word refer to non-neuronal tissue.
- Neurinoma (Neurilemmoma) - a benign slow growing tumor of the neurolemma (myelin sheath) of a nerve fibre.
- Ganglioneuroma could be considered a type of neuroma, though it is not a nerve sheath tumor.
In its most general sense, neuroma
can be applied to any swelling of a nerve. Thus, there are a variety of usages that don't refer to neoplastic
- Traumatic neuroma follows different forms of nerve injury (often as a result of surgery). They occur at the end of injured nerve fibres as a form of uneffective, unregulated nerve regeneration; it occurs most commonly near a scar, either superficially (skin, subcutaneous fat) or deep (e.g., after a cholecystectomy). They are often very painful. It is also known as "pseudoneuroma".
- Morton's neuroma (a mononeuropathy of the foot) is another example of the older, more general usage of neuroma. Some prefer the term "Morton's metatarsalgia", thus avoiding the term neuroma and its association with tumors.