Nega'im (Hebrew: נגעים, Blemishes) is the third tractate of the order of Tohorot in the Mishnah. It consists of fourteen chapters. Nega'im describes the various forms of tzaraath, a leprosy-like disease described in the Bible (Leviticus 13-14), which affected people, clothing, and homes. The tractate describes the different types of blemishes symptomatic of the disease, and the various rituals involved in purifying someone who has been affected by it.

There is no Gemara for Nega'im in either the Babylonian or Jerusalem Talmud.

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