is a surname and may refer to:
- Robert Mosbacher (b. 1927), U.S. businessman and United States Secretary of Commerce
- Robert Mosbacher, Jr., businessman and Republican politician and is the current head of the Overseas Private Investment Corporation. Son of Robert Mosbacher
- Georgette Mosbacher (b. 1947), American businesswoman and Republican fundraiser. Former wife of Robert Mosbacher.