• Datura species, including D. inoxia, from the Solanaceae
• Hylocereus species, from the Cactaceae
• Ipomoea species previously separated in Calonyction, including I. alba and I. turbinata, from the Convolvulaceae
• Mentzelia species, including M. pumila (Velcro Stickleaf), from the Loasaceae

Moonflower can also refer to:

In music:

• Moonflower (album), a 1977 rock album by Carlos Santana.
• Moon Flower (album), a 2008 rock album by The Underneath.

In stage lighting:

• A representative of one specific class of stage lighting instruments#Intelligent_lights.