The word chloride can also refer to a chemical compound in which one or more chlorine atoms are covalently bonded in the molecule. This means that chlorides can be either inorganic or organic compounds. The simplest example of an inorganic covalently-bonded chloride is hydrogen chloride, HCl. A simple example of an organic covalently-bonded (an organochloride) chloride is chloromethane (CH3Cl), often called methyl chloride.
In the petroleum industry, the chlorides are a closely monitored constituent of the mud system. The increase of the chlorides in the mud system could indicate the possibility of drilling into a high-pressure saltwater formation. Its increase can also indicate the poor quality of a target sand.
Other examples of inorganic covalently-bonded chlorides that are used as reactants are:
Chloride ions have important physiological roles. For instance, in the central nervous system, the inhibitory action of glycine and some of the action of GABA relies on the entry of Cl− into specific neurons. Also, the chloride-bicarbonate exchanger biological transport protein relies on the chloride ion to increase the blood's capacity of carbon dioxide, in the form of the bicarbonate ion.
The normal blood reference range of chloride for adults in most labs is 95 to 105 milliequivalents (mEq) per liter. The normal range may vary slightly from lab to lab. Normal ranges are usually shown next to your results in the lab report.
The North American Dietary Reference Intake recommends a daily intake of between 2300 and 3600 mg/day for 25-year-old males.