Acute mediastinitis is usually bacterial and due to rupture of organs in the mediastinum. As the infection can progress rapidly, this is considered a serious condition. Chronic sclerosing (or fibrosing) mediastinitis, while potentially serious, is caused by a long-standing inflammation of the mediastinum, leading to growth of acellular collagen and fibrous tissue within the chest and around the central vessels and airways. It has a different cause, treatment, and prognosis than acute infectious mediastinitis.
Treatment usually involves aggressive intravenous antibiotic therapy and hydration. If discrete fluid collections (such as abscesses) have formed, they may have to be surgically drained.
Treatment for chronic fibrosing mediastinitis is somewhat controversial, and may include steroids or surgical decompression of affected vessels.
Risk factors for mediastinitis after cardiac surgery - a retrospective analysis of 1700 patients.(Research article)(Clinical report)
May 20, 2007; Authors: Claudius Diez (corresponding author) (equal contributor) ; Daniel Koch ; Oliver Kuss ; Rolf-Edgar Silber ;...
Findings from Catharina Hospital, Department of Cardiothoracic Surgery provide new insights into mediastinitis risk factors.(Report)
Mar 28, 2010; New research, 'Preoperative atrial fibrillation and elevated C-reactive protein levels as predictors of mediastinitis...