, a lyase
is an enzyme
that catalyzes the breaking of various chemical bonds
by means other than hydrolysis
, often forming a new double bond
or a new ring structure. For example, an enzyme that catalyzed this reaction would be a lyase:
- ATP → cAMP + PPi
Lyases differ from other enzymes in that they only require one substrate for the reaction in one direction, but two substrates for the reverse reaction.
Systematic names are formed as "substrate group
lysase." Common names include decarboxylase
, etc. When the reverse reaction is more important, synthase
may be used in the name.
Lysases are classified as EC 4
in the EC number
classification of enzymes. Lyases can be further classified into seven subclasses: