lupus

lupus

[loo-puhs]
lupus, noninfectious chronic disease in which antibodies in an individual's immune system attack the body's own substances. In lupus, medically known as lupus erythematosus, antibodies are produced against the individual's own cells, causing tissue inflammation and cell damage. Because the vascular and connective tissue of any body organ may be affected, various symptoms may result. Generalized symptoms include fever, weakness, weight loss, anemia, enlargement of the spleen, and a characteristic butterfly-shaped skin rash on the face. Heart, joint, and kidney disease are common (see nephritis). It is believed that the disease may be triggered by certain drugs or foreign proteins, exposure to ultraviolet radiation, or extreme stress. The disease, which may range from mild to fatal, occurs commonly in young women. It is treated with immunosuppressive drugs and steroids. See immunity; autoimmune disease.

See R. G. Lahita and R. H. Phillips, Lupus: Everything You Need to Know (1998).

Either of two inflammatory autoimmune diseases, both more common in women. In the discoid type, a skin disease, red patches with grayish brown scales appear on the upper cheeks and nose (often in a butterfly pattern), scalp, lips, and/or inner cheeks. Sunlight worsens it. Antimalarial drugs may help. The second type, systemic (disseminated) lupus erythematosus (SLE), may affect any organ or structure, especially the skin (with marks like those of the discoid type), kidneys, heart, nervous system, serous (moisture-forming) membranes (e.g., in synovial joints or lining the abdomen), and lymph nodes, with acute episodes and remissions. Symptoms vary widely. Kidney and central-nervous-system involvement can be life-threatening. Treatment includes pain relief, control of inflammation, and trying to limit damage to vital organs.

Learn more about lupus erythematosus with a free trial on Britannica.com.

Lupus is a city in Moniteau County, Missouri, United States. The population was 29 at the 2000 census, at which time it was a town. The town was originally named Wolfe's Point. However, when it was discovered that another town in Missouri had a similar name the town was forced to change their name. A local school teacher suggested Lupus. Lupus is latin for wolf. The city is most well known for its chili festival, held every autumn, which draws several hundred people from the surrounding area. The 1973 musical Tom Sawyer based on Mark Twain's novel was shot partially on location here. In 1976 the school of journalism at the University of Missouri wrote a book of photo essays on the history and the diminishing population of the town titled Lupus: portrait of a Missouri river town.

Geography

Lupus is located at (38.846609, -92.452641).

According to the United States Census Bureau, the town has a total area of 0.2 square miles (0.5 km²), all of it land.

Demographics

As of the census of 2000, there were 29 people, 18 households, and 5 families residing in the town. The population density was 150.8 people per square mile (58.9/km²). There were 24 housing units at an average density of 124.8/sq mi (48.8/km²). The racial makeup of the town was 100.00% White.

There were 18 households out of which 16.7% had children under the age of 18 living with them, 16.7% were married couples living together, 16.7% had a female householder with no husband present, and 66.7% were non-families. 61.1% of all households were made up of individuals and 22.2% had someone living alone who was 65 years of age or older. The average household size was 1.61 and the average family size was 2.50.

In the town the population was spread out with 20.7% under the age of 18, 3.4% from 18 to 24, 10.3% from 25 to 44, 51.7% from 45 to 64, and 13.8% who were 65 years of age or older. The median age was 49 years. For every 100 females there were 123.1 males. For every 100 females age 18 and over, there were 91.7 males.

The median income for a household in the town was $18,750, and the median income for a family was $18,750. Males had a median income of $23,750 versus $63,750 for females. The per capita income for the town was $19,341. None of the population and none of the families were below the poverty line.

References

External links

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