Definitions

lunate fracture

Kienbock's disease

Kienbock's disease is a disorder of the wrist. It is named for Dr. Robert Kienböck, a radiologist in Vienna, Austria who described osteomalacia of the lunate in 1910.

It is breakdown of the lunate bone, a carpal bone in the wrist that articulates with the radius in the forearm. Specifically, Kienbock's disease is another name for avascular necrosis (death and fracture of bone tissue due to interruption of blood supply) with fragmentation and collapse of the lunate. This has classically been attributed to arterial disruption, but may also occur after events that produce venous congestion with elevated interosseous pressure.

Predisposing factors

There are thought to be a number of factors predisposing a person to Kienbock's.

Recent studies have made a correlation between Kienbock's sufferers and Western European ancestry, but no definitive link can be positively confirmed.

The necrosis of the lunate bone can frequently be traced to a trauma to the wrist, like a compound fracture, which could cause the lunate's blood supply to be interrupted. There has also been documentation showing that some people have only one artery supplying the lunate, which could be easily severed or pinched, even through a slight sprain, causing the patient to develop Kienbock's. Despite a preponderance of evidence, no particular etiology has been conclusively verified.

Data exists on the internet that most people suffering from Kienbock's are affected in their dominant hand, though about one-third of sufferers report the condition in their non-dominant hand.

Kienbock's disease is classified as a "rare disorder," meaning that it affects less than 200,000 people in the U.S. population.

Many Kienbock's patients are frustrated by the lack of consensus among hand surgeons about optimal treatments for Kienbock's. No matter what the disease's stage of progression, there is no one best treatment, and the decision is often based partially, or even mostly, on incidental factors such as the patient's pain tolerance, the patient's desire to return to active use of the hand (such as in manual occupations), and the surgeon's level of expertise with different treatments.

Classification Scheme

Kienbock's disease is classified by features that indicate the severity of the problem.

  1. Normal radiograph (possible lunate fracture).
  2. Sclerosis of the lunate without collapse.
  3. Lunate collapse, fragmentation.
  4. Changes up to and including fragmentation, with superimposed arthritic changes.

Treatment

Operations that attempt to restore a blood supply to the lunate may be performed.

Depending on the stage the disease is in when it is discovered, varying treatments are applied.

If X-rays show a mostly intact lunate (not having lost a great deal of size, and not having been compressed into a triangular shape), but an MRI shows a lack of blood flow to the bone, then revascularization is normally attempted. Revascularization techniques, usually involving a bone graft taken elsewhere from the body - often held in place by an external fixator for a period of weeks or months - have been successful at stages as late as 3B, although their use at later stages (like most treatments for Kienbock's) is controversial.

Some Kienbock's patients present with an abnormally large difference in length between the radius and the ulna, termed "ulnar variance", which is hypothesized to cause undue pressure on the lunate, contributing to its avascularity. In cases with such a difference, radial shortening is commonly performed. In this procedure, the radius (the inside long bone) is shortened by a given length, usually between 2 and 5 mm, to relieve the pressure on the dying lunate. A titanium plate is inserted to hold the newly shortened bone together.

During Stage 3, the lunate has begun to break apart due to the pressure of the surrounding bones. This causes sharp fragments of bone to float between the joints, causing excruciating pain. At this point, the lunate is ready for removal. The most frequently performed surgery is the Proximal Row Carpectomy, where the lunate, scaphoid and triquetrum are extracted. This greatly limits the range of motion of the wrist, but pain relief can be achieved for longer than after the other surgeries.

Another surgical option for this stage is a titanium or silicon implant that takes place of the lunate, though doctors shy from this due to a tendency of the implant to smooth the edges of the surrounding bones, thus causing painful pinched nerves when the bones slip out of place.

After the lunate is removed, another procedure, ulnar shortening can be performed. This relieves pressure on the newly formed wrist joint of the pisiform, hamate and capitate. Depending on the surgeon, the procedure may be performed the same way as the radial shortening where a small section is removed, or the entire top of the ulna may be excised.

At Stage 4, the lunate has completely disintegrated and the other bones in the wrist have radiated downward to fill in the void. The hand now has a deformed, crippled appearance. The only procedure that can be done is the total wrist fusion, where a plate is inserted on the top of the wrist from the radius to the carpals, effectively freezing all flexion and movement in the wrist. Rotation is still possible as it is controlled by the radius and ulna.

This is currently the last and most complete surgical option for Kienbock's sufferers.

Most of the treatments described here are not mutually exclusive - meaning that a single patient may receive many of them in his quest to relieve pain. For instance, some patients have had casting, bone graft, radial shortening, proximal row carpectomy, and wrist fusion, all on the same hand.

References

External links

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