Rain gutter, a narrow channel which collects rainwater from the roof of a building and diverts it away from the structure, typically into a drain.
Street gutter, a depression which runs alongside a city street, usually at the curb and diverts rain and street-cleaning water away from the street and into a storm drain.
In media
Gutter (comic), a British adult-oriented comic from the 1990s
In sport
Gutters, in bowling and table shuffleboard, the trough hazards on either side of the playing lane into which the bowling ball or shuffleboard puck may fall
In design and printing
Gutter, the blank space, in editorial design, at which two pages come together in a two-page spread
Gutter, in typography, the space between columns of printed text
Gutter, in comics, the space between the panels of a comic strip or comic book page
Gutter (philately), the space between panes of postage stamps that creates configurations of "gutter pairs" or "gutter blocks"
Gutter, in interface design, the blank spaces that separate rows and columns in screen. Sometimes, uses small graphic file which has background color to make space for layout.