lipids, a broad class of organic products found in living systems. Most are insoluble in water but soluble in nonpolar solvents. The definition excludes the mineral oils and other petroleum products obtained from fossil material. Major classes of lipids include the
fatty acids, the glycerol-derived lipids (including the
fats and oils and the
phospholipids), the sphingosine-derived lipids (including the ceramides, cerebrosides, gangliosides, and sphingomyelins), the
steroids and their derivatives, the terpenes and their derivatives, certain aromatic compounds, and long-chain alcohols and
waxes. In living organisms lipids serve as the basis of
cell membranes and as a form of fuel storage. Often lipids are found conjugated with proteins or carbohydrates, and the resulting substances are known as
lipoproteins and lipopolysaccharides. The fat-soluble
vitamins can be classified as lipids.
Liposomes are spherical vesicles formed by mixing lipids with water or water solutions. They have found applications in the oral administration of some drugs (e.g., insulin and some cancer drugs), since they retain their integrity until they are broken down by the
lipases in the stomach and small intestine.
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