Jean Preston (Patricia Morison) is determined to find her fiancée, Greg Jones (Bruce Edwards), who went on a safari and didn’t come back when expected. She travels to Akbar, India with With Greg’s father, Colonel Jones (John Miljan), Wayne Monroe (Keith Richards, no relation) and the Professor (Wilson Benge). She asks about Jones at the front desk of the hotel where she stays. Although the clerk acts like he knows nothing of Jones, he immediately makes a suspicious phone call when the group leaves the lobby.
While Jean unpacks in her room, a native woman named Tondra (Vida Aldana), who spied on the group in the hotel lobby earlier, knocks on the door. She tells Jean that her husband, Moya (Hassam Kayyam), spoke to her of a safari that suffered a tiger attack. Jean asks Tondra to speak to her husband. Although apprehensive to get her husband at first, she quickly fetches her husband when Jean greases her palm. Tondra returns with Moya, who recognizes Jones from a photo of Jean’s. He tells Jean that Jones traveled not with the doomed safari but with a group of ivory hunters that went to Africa. Before Moya can say more, someone shoots him with a pistol through Jean’s room window. The shooting upsets the unstable locals and the group leaves for Africa.
They take a boat deep into the African jungle where they see some beautiful stock footage. Jean must convince Gary Lambert (Robert Lowery), who hates taking women on safaris, to be their guide. She knocks his socks off with her shooting skills with a gun. They also pick up famed safari cook, Gabby (J. Edward Bromberg), who likes to recite poetry to his pet monkey and tells stories with belligerent verbosity, which he mistakes for skill. The Commissioner (of what is not made clear) tells Lambert that Jones was on a mission to bust Ivory poachers and wants Lambert to do the same, which Lambert readily agrees.
The rescue mission meets with turmoil and death. The mishaps the group experiences connect to an unknown saboteur among their ranks. A native man tells the group rumors of a group of white she-devils in the jungle that make their native guides skittish. The women came from a lifeboat from a shipwreck many years ago. If all that wasn’t bad enough, when Greg is found, it’s revealed he fell for the white she-devil queen, Zita (Amira Moustafa), who doesn’t plan on giving him up.