Mycale resulted in the destruction of the main Persian forces in Ionia, as well as their Mediterranean fleet.
The Battle of Plataea on the same day on the Greek mainland was a victory as well, and the Persians were forced to leave both Greece and Ionia and retreat inland, thereby ending Persian rule.
The battle is known to history through the writings of Herodotus of Halicarnassus.
While the Spartans prepared for war, eventually mustering a force of 5,000 and another 35,000 allies, a delegation from Samos arrived in Sparta asking for help. The Greek fleet of 110 ships set sail from Delos under the command of Leotychides.
Men of Ionia—ye who can hear me speak—do ye take heed to what I say; for the barbarians will not understand a word that I utter. When we join battle with them, before aught else, remember Freedom—and next, recollect our watchword, which is Hebe. If there be any who hear me not, let those who hear report my words to the others.|15px|15px|Herod. 9.98
Realizing generally what was going on, the Persians disarmed the Samians and sent their enemies, the Milesians, to guard the roads to the rear. Meanwhile the Greeks unloaded their ships and formed up for combat. As usual the Spartans occupied the right wing, placing the Athenians on the left. The Athenians, walking along the beach, found a herald's scepter and thought that it is a divine sign, signifying that the other Greeks had been victorious on the mainland. They then charged forward to the attack alone, and after a short battle the Persians, led by Artaÿntes, were forced to retreat to the fort they had constructed further inland. The Athenians chased them and captured the fort as well. The Persian survivors fled, only to find that the Milesian rear-guard had turned against them as well, and few survived to eventually reach Sardis.
When the Spartans arrived the Persian camp was looted and their beached ships destroyed. Returning to Samos they then discussed their next moves. The Spartans proposed that they evacuate the cities of the Ionian Greeks and bring the population to the Greek mainland, as they did not consider it worth their trouble to defend the Ionians every time they were attacked. The Athenians, however, objected to losing their colonies, and accepted the Ionian Greeks in a league against Persia.