Slicked-up Pup is a 1951 one-reel animated cartoon and is the 60th Tom and Jerry cartoon directed by William Hanna and Joseph Barbera and produced by Fred Quimby. The cartoon was scored by Scott Bradley and animated by Ed Barge, Kenneth Muse, Irven Spence and Ray Patterson. It features the second appearance of both Spike and Tyke together.
Spike has just bathed Tyke so that he is nice and clean. Leaving his boy lying in the sun to "soak up some of that good sunshine vitamin," Spike is horrified when, through the constant chases of Tom and Jerry, Tyke ends up getting dirty by falling into a muddy puddle. Spike grabs Tom and scolds him. "What's the idea, messing up my boy?! Go clean him up!" He yells. Tom quickly rushes off with the muddy pup and returns almost instantly with Tyke cleaned up. " Now put him down! Listen, pussy cat! He's clean now, and he better be clean when I get back! An' if he ain't, I'll tear ya limb from limb! Understand?!" Spike walks off angrily.
Tom grudgingly agrees to look after the pup and ensure his cleanliness until Spike returns. As Tom sits down on the same wooden platform that Tyke is lying on, one of the wooden planks catapults Tyke into the air, and Tom narrowly saves Tyke from falling into the same muddy puddle. Tom breathes a sigh of relief and wipes some sweat from his brow, which ends up on Tyke's face. In a panic, Tom rapidly rubs it off with a handkerchief and sprays detergent on him until he ends up sparkling. Tom overhears Jerry's laughter and chases after him. Jerry quickly stops the cat, and challenges him to a game of tic-tac-toe - on Tyke's back. Tom wins (Jerry may have let him win, however) and resumes chasing Jerry, before suddenly realizing what he's done, and promptly returns to Tyke to rub off his pencil marks. Jerry hurls a tomato at Tom, but Tom quickly ducks so that it avoids him, then realizes that it will hit Tyke instead. Tom rushes back and stands directly in front of the pup so that the tomato does hit him after all. The chase resumes, until Jerry threatens to spill a jar of ink over Tyke. Tom slowly backs off, but when out of Jerry's sight, he jumps through an open window, comes up behind Jerry and snatches the ink off him. He throws the ink up into the air, but it falls on the roof, rattles down a drainpipe and out again, spilling onto Tyke.
Tom panics once again after seeing Tyke covered in ink, and grabs some paint tins, painting Tyke white. He then uses another paintbrush to paint Tyke brown, but Jerry pushes the paint containers so that Tom ends up dipping his paintbrush into a variety of different colors, rendering Tyke a multi-colored mess of reds, blues, greens and yellows. Horrified, Tom grabs a hose so that he can wash the paint off, but crafty Jerry connects the other end of the hosepipe to a large container of tar. Out of the hosepipe comes thick, black, sticky tar. Tom sees that Spike is approaching, and decides that he has to act quickly or suffer the consequences. He spots a pillow hanging on a washing line, and stuffs Tyke into it and takes him out, leaving Tyke covered in feathers. He then places a red glove on Tyke's head and a clothes peg on his mouth, so that Tyke crudely resembles a chicken of sorts. Spike is surprisingly fooled. "Where's my boy?" he asks, gruffly. Tyke protests in a panicked manner, and Spike looks at Tom suspiciously. Tom then recovers by manipulating Tyke into making chicken actions and pecking on the ground and a strained "cock-a-doodle-doo!" sound. Convinced, Spike walks off. However, Tyke removes the peg from his mouth and bites Tom's tail. Tom lets out a piercing scream, and Spike is alerted.
Tom rushes off and hides in the laundry room, putting Tyke inside a washing machine. Just as Tom is adding soap flakes, he is stopped by Spike, who takes Tyke out of the washing machine. Moments after Tyke sneezes due to his allergy to soap flakes, Spike angrily pours the box of soap flakes over Tom's head and shoves a soap bar in his mouth, before chucking Tom in the washing machine and slamming the door on him.
The cartoon ends with Tom being spun around the washing machine as Spike, Tyke and Jerry look on.