Technology

• ICS (Jacksonville), a computer services company in Jacksonville, Florida, originally Information Computing Services
• Information and Communications Support
• Internet Computing Service, a utility computing service for data storage, network, and cpu resources
• Incident Capturing System
• Image Correlation Spectroscopy
• Image Cytometry Standard, a digital multidimensional image file format used in life sciences microscopy
• Information and Computer Science, the combined field of informatics and computing.
• InterCitySlovenija, a High Quality Train Service in Slovenia Ù
• InterCitySlovenija - ETR 310 Pendolino Tilting Trains in Slovenia
• International Classification for Standards, an international classification system for technical standards
• inter carrier spacing
• Internet Caching System, a set of components for building an electronic business infrastructure. It is reverse proxy
• Internet chess server, an external server that provides the facility to play, discuss, and view chess over the Internet
• Internet Component Suite, component library by Belgian François Piette for Delphi and C++Builder
• Internet Connection Sharing, a feature in Microsoft operating systems since the advent of Windows 98 Second Edition
• iCalendar, the RFC 2445 standard for calendar data exchange
• Israeli Cassini Soldner, a historical geographic coordinate system
• IMS Centralized Services, a concept developed by 3GPP in TR 23.892
• Inventory Control Specialists

Organizations

• Illawarra Christian School, New South Wales, Australia
• Incident Command System, an emergency response management system
• Immersion Composition Society, a network of speed-composers
• Immaculate Conception School, one of several catholic schools in the United States
• Indian Central School, formally known as "Global Indian International School Singapore", a school in Singapore
• Indian Civil Service, a unit of the government of India
• Institute for Curriculum Services
• Institute of Cornish Studies
• Instituto de Ciências Sociais (Institute of Social Sciences), a research institute of the University of Lisbon
• Integrated Circuit Systems, an American integrated circuit manufacturer(PCI vendor ID 117F), now part of IDT
• Integrated Computer Solutions, a US software development and professional services organization
• Inter-Community School Zürich, an international school in Zurich, Switzerland.
• International Chamber of Shipping
• International Christian School, an international school located in Hong Kong.
• International Church of Stockholm, an organization in Church of Sweden to give English services
• International College of Spain, a private international school in Madrid, Spain
• International Commission on Stratigraphy, the largest scientific body within the International Union of Geological Sciences
• Immigration And Customs Security, A fictional organization in a CBC series called The Border
• International Community School is the name of several schools
• International Conference on Super Computing, a computer science conference
• Internet Consulting Services, a technology provider in Ames, Iowa, USA
• Graduate School of International Corporate Strategy, the business school of Hitotsubashi University in Tokyo, Japan
• Iranian Cheetah Society, a society dedicated to the protection of the endangered Iranian cheetah
• Irish Computer Society, the national body for Information and Communication Technology (ICT) Professionals in Ireland
• Islami Chhatra Shibir, student wing of the Islamist political party, Jamaat-e-Islami, of Bangladesh.
• Islamic Charitable Society, a terrorist group operating under the guise of a charitable organisation

Medicine

• Immotile cilia syndrome, also known as "Primary ciliary dyskinesia", a rare human genetic disorder
• Inhaled corticosteroid, a delivery method for certain pharmaceutical drugs

Other

• Incident Command System, a standardized, on-scene, all-hazard incident management concept in the United States
• ICS Vortex, the Norwegian black metal musician Simen Hestnæs
• International Code of Signals, a maritime signaling standard also abbreviated INTERCO