GLUT1 was the first glucose transporter to be characterized. It is widely distributed in fetal tissues. In the adult it is expressed at highest levels in erythrocytes and also in the endothelial cells of barrier tissues such as the blood-brain barrier. Glut1 is a major receptor for take-up of Vitamin C as well as glucose, especially in non vitamin C producing mammals as part of an adaptation to compensate by participating in a Vitamin C recycling process. In mammals that do produce Vitamin C Glut4 is often expressed instead of Glut1.
Limitations of empirical therapy for bacterial meningitis in a healthy child with Listeria monocytogenes meningitis
Jan 01, 2006; Abstract. Whilsl Lisicria monocyiogenex (L. monocyiogenex) meningitis is more common in neonates and the immunosuppressed....