Holmium(III) oxide, is a chemical compound with the formula Ho2O3. It is sometimes used in making specialty glasses. Together with dysprosium(III) oxide (Dy2O3) holmium oxide is one of the most powerfully paramagnetic substances known. The oxide, also called holmia, occurs as a component of the related erbium oxide mineral called erbia. Typically the oxides of the trivalent lanthanides coexist in nature. The separation of these components requires specialized methods.
It is often used to calibrate spectrophotometers, due to its spectral and absorption properties. It is also used in control rods in nuclear reactors, since it can absorb neutrons.
Treating holmium oxide with hydrogen chloride affords the corresponding holmium chloride.