It is the most widespread and common species of the group, being found in many different kinds of environments, including evergreen and dry forests and in highly perturbed natural areas.
It is a solitary, nocturnal and diurnal animal, feeding on leaves of many species of trees.
The female of the species is known to emit a loud, shrill scream during the mating season to attract males. It is a cry that sounds like "ay ay". This scream has been remarked to sound exactly like that of a woman screaming.
The sloth has grayish brown to beige color fur and it is very coarse and stiff. A sloth has a round head and on it there are two eyes, a blunt nose, peg-like teeth, and ears that are not visible. The tail of a sloth is very small.
Over parts of its range, the Brown-throated Three-toed Sloth overlaps the range of Hoffmann's Two-toed Sloth. Where this overlap occurs, the three-toed sloth tends to be smaller and more numerous than its relative, being more active in moving through the forest and maintaining more diurnal activity.