In biology, gonochorism (Greek offspring + disperse) or unisexualism describes sexually reproducing species in which there are at least two distinct sexes. The sex of an individual is most often genetically determined and does not usually change throughout its lifetime. (Clownfish and alligators are good examples of exceptions. Male Clown fish can change their sex during their lifetime and the sex of an alligator can be determined by the incubation temperature of its egg.) Good examples of this type of pollination are hollies, and kiwifruit. In these plants the male plant which supplies the pollen is referred to as the pollenizer. The vast majority of mammals, for example, are gonochorists.

Gonochorism stands in contrast to other reproductive strategies such as hermaphroditism.

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