Definitions
glycerol&o=10616

1-alkyl-2-acetylglycerol O-acyltransferase

In enzymology, a 1-alkyl-2-acetylglycerol O-acyltransferase is an enzyme that catalyzes the chemical reaction

acyl-CoA + 1-O-alkyl-2-acetyl-sn-glycerol rightleftharpoons CoA + 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol

Thus, the two substrates of this enzyme are acyl-CoA and 1-O-alkyl-2-acetyl-sn-glycerol, whereas its two products are CoA and 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol O-acyltransferase. This enzyme is also called 1-hexadecyl-2-acetylglycerol acyltransferase. This enzyme participates in ether lipid metabolism.

References

  • Kawasaki T, Snyder F "Synthesis of a novel acetylated neutral lipid related to platelet-activating factor by acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol acyltransferase in HL-60 cells". J. Biol. Chem. 263 2593–6.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes

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