B. coagulans is a Gram-positive, spore-forming, motile rod (0.9μm by 3.0μm to 5.0μm in size), aerobic to microaerophilic and as all other species in genus Bacillus, forms endospores, which are resistant to chemical and physical agents. It may appear Gram-negative when entering the stationary phase of growth. The temperature optimum for growth is 50 °C. IMVic Tests VP and MR (methyl-red) tests are positive. Citrate and Nitrate tests are negative.
Bacillus coagulans has been approved for veterinary purposes as GRAS by the FDA's Center for Veterinary Medicine, as well as by the EU and is listed by AAFCO for use as a direct fed microbial in livestock production. Its main use is thus is veterinary applications, especially as a probiotic in pigs and shrimp. There are some references to use of this bacterium in humans, especially in improving the vaginal flora. On activation of spore formation in the acidic environment of the stomach, this organism can germinate and proliferate in the intestine.
Bacillus coagulans is often marketed as Lactobacillus sporogenes or a 'sporeforming lactic acid bacterium' probiotic , but this is an outdated name due to taxonomic changes in 1939. Although Bacillus coagulans does produce L+ lactic acid, the bacterium used in these products is not a lactic acid bacterium, as Bacillus species do not belong to the lactic acid bacteria. By definition, lactic acid bacteria (Lactobacillus, Bifidobacterium) do not form spores. Therefore, using the name 'Lactobacillus sporogenes' is scientifically incorrect.
WIPO ASSIGNS PATENT OF AMANO ENZYME FOR "REDUCING AGENT FROM MICROORGANISM BELONGING TO GENUS BACILLUS AND APPLICATION FOR SAME" (JAPANESE INVENTORS)
Nov 19, 2011; GENEVA, Nov. 19 -- Publication No. WO/2011/142300 was published on Nov. 17. Title of the invention: "REDUCING AGENT FROM...