Gash-Barka (ጋሽ-ባርካ) is one of the six regions of Eritrea. It is situated in the south-west of the country, bordering the Anseba region to the north, and the Central and Southern regions to the east; the county of Sudan lies to the west and Ethiopia to the south.
With an area of 37,000 square kilometers and a population of 567,000, the Gash Barka region makes up roughly one-third of Eritrea. Many call this region the "breadbasket" as the region is very rich in agriculture. As of 2005, many believe there are over 3.5 million livestock in this region, and many camels. The region is also very rich in marble, and other important minerals, including gold. In Augaro, there are some old mineshafts and machinery from the days when the Italians mined gold here.
Almost all the people in the area tend to be healthy and well-fed, a rarity in this area of Africa.
The region also includes the following districts: