Fungemia

Fungemia

Fungemia (also known as Candidemia, Candedemia, and Invasive Candidiasis) is the presence of fungi or yeasts in the blood. It is most commonly seen in immunosuppressed or immunocompromised patients with severe neutropenia, oncology patients, or in patients with intravenous catheters. Recently, it has been suggested the otherwise immunocompetent patients taking infliximab may be at a higher risk for fungemia.

The diagnosis is complicated, as routine blood cultures have poor sensitivity.

Treatment

Treatment involves use of antifungals, e.g. fluconazole or amphotericin.

Risk factors

The two most important risk factors are:

Other risk factors are:

Pathogens

The most commonly known pathogen is Candida albicans, causing roughly 70% of fungemias, followed by Candida glabrata with 10%, and Aspergillus with 1%. However, the frequency of infection by T. glabrata, Candida tropicalis, C. krusei, and C. parapsilosis is increasing, especially when significant use of fluconazole is common.

Symptoms

Symptoms can range from mild to extreme, often described as extreme flu-like symptoms. Pain, mental disorders, chronic fatigue, infections, are a few of the long list of associated symptoms with Fungemia.

See also

External links

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