Formed by and led by David Cunningham, the group included avant-garde and free improvising musicians, such as David Toop and Steve Beresford as instrumentalists, plus Deborah Evans-Stickland and Patti Palladin as main vocalists. It also boasted Michael Upton.
The group released an album entitled The Flying Lizards in 1979; their singles include the postmodern cover versions of songs such as Eddie Cochran's "Summertime Blues" (1978) and James Brown's "Sex Machine" (1984), as well as several originals. Their album Top Ten consists entirely of covers, done in a deliberately emotionless, harsh and robotic style. Their version of Barrett Strong's "Money" remains popular, and was used in the film soundtracks for The Wedding Singer, Empire Records, Charlie's Angels and Lord of War, as well as in the Emmy and Golden Globe award-winning American television medical drama, Nip/Tuck.
With only one single making the UK Top 40, the Flying Lizards join the list of one-hit wonders; a list that includes other UK punk or new wave acts such as The Banned, John Cooper Clarke, Jilted John, 999, the Radio Stars, the Rich Kids and The Vibrators.