, a (R)-2-hydroxy-fatty-acid dehydrogenase
is an enzyme
the chemical reaction
- (R)-2-hydroxystearate + NAD+ 2-oxostearate + NADH + H+
Thus, the two substrates of this enzyme are (R)-2-hydroxystearate and NAD+, whereas its 3 products are 2-oxostearate, NADH, and H+. This reaction is important in fatty acid metabolism.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-2-hydroxystearate:NAD+ oxidoreductase. Other names in common use include D-2-hydroxy fatty acid dehydrogenase, and 2-hydroxy fatty acid oxidase.
- Levis GM "2-Hydroxy fatty acid oxidases of rat kidney". Biochem. Biophys. Res. Commun. 38 470–7.
- The CAS registry number for this enzyme class is .
Gene Ontology (GO) codes