There are several ways to add a reference to a library: manually, exporting, importing, connecting from EndNote. The program presents the user with a window containing a drop-down menu to select the type of reference they require (book, newspaper article, film, congressional legislation, etc.), and fields ranging from the general (author, title, year) to those specific to the kind of reference (ISBN number, abstract, reporter's name, running time, etc.) Most bibliographic databases allow users to export references to their EndNote libraries. This enables the user to select multiple citations and saves the user from having to manually enter the citation information and the abstracts. There are some databases (e.g. PubMed) in which the user needs to select citations, select a specific format, and save them as .txt files. By then going to EndNote, the user can then import the citations into the EndNote software. It is also possible to search library catalogs and free databases such as PubMed from within the EndNote software program itself.
If the user fills out the necessary fields, EndNote can automatically format the citation into whatever format the user wishes from a list of over two thousand different styles.
For example, a citation for an edition of Gray's Anatomy in a few different styles:
| Anthropos | Gray, Henry 1910 Anatomy, descriptive and applied. Philadelphia: Lea & Febiger. [18th ed.] |
| APA 5th | Gray, H. (1910). Anatomy, descriptive and applied (18th ed.). Philadelphia: Lea & Febiger. |
| MLA | Gray, Henry. Anatomy, Descriptive and Applied. 18th ed. Philadelphia: Lea & Febiger, 1910. |
| New England J Medicine | 1. Gray H. Anatomy, descriptive and applied. 18th ed. Philadelphia: Lea & Febiger; 1910. |
Under Windows, EndNote saves a file with the *.enl or extension along with a *.data folder containing various MySQL files with *.myi and *.myd extensions. EndNote can optionally be installed such that its functionality appears in the Tools menu of Microsoft Word for "cite while you write" and other functions.
EndNote can export citation libraries as plain text, Rich Text Format, HTML or XML. The current version of EndNote has networking capabilities, and files can reside on a central server. It does not, however, have multi-user capabilities for editing a single bibliographic file.
Endnote can also organize PDFs on your hard-disk (or full-text on the web) through links to files or by inserting copies of PDFs. It is also possible to save a single image, document, excel sheet, or other file type to each reference in an EndNote library. Starting from EndNote X version 1.0.1 formatting support for OpenDocument files (ODT) using the Format Paper command is supported.
Also, the program might not always detect redundancies if data is not entered properly. For example, if for a newspaper article you enter "2005" for the Year field and then "April 7, 2005" for the Date field EndNote might actually output the date as "April 7, 2005 2005"
Filters, which allow for the seamless transport of citation data into the EndNote reference, may need to be updated. EndNote maintains a page with the corrected versions of the filters.
The Cite While You Write feature in EndNote is not compatible with 64-bit versions of Windows.
EndNote X1 runs natively on both PPC and Intel-based Macs. The Cite While You Write feature of EndNote X1 for Mac OS is only compatible with Word 10.1.2-10.1.6 and Word 2004. Due to changes in the way third party addins are supported in Word 2008, Cite While You Write is not natively compatible with Word 2008. A patch was released on June 26th 2008 that restores cite while you write functionality to Word 2008.
It cannot directly import BibTex files, but there are various third-party methods to transform these into the refer format, which may be imported.