Effective renal plasma flow

Effective renal plasma flow

Effective renal plasma flow (eRPF) is a measure used in renal physiology to calculate renal plasma flow (RPF) and hence estimate renal function.

eRPF = RPF times extraction ratio

Where extraction ratio is the ratio of compound entering the kidney that got excreted into the final urine.

When using a compound with an extraction ratio near 1, such as para-aminohippurate (PAH), then eRPF is almost equal to RPF. Therefore, PAH clearance is a method to estimate renal plasma flow.


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