The song is an "epic weepy" anthem in the spirit of "Don't Look Back in Anger", reassuringly advising that in times of hardship, simply get over it and get on with your life. Noel Gallagher explained the song saying "A friend of mine was going through a pretty bad time and I sort of wrote it with him in mind."
Noel Gallagher had great expectations for the song, saying "I hope it does for us what 'Don't Look Back In Anger' did... I didn't want it as a single because I thought we'd done all that before, but everyone's going, 'You're fucking mad.'". NME said, 'Stop Crying Your Heart Out' [is where] you really start rolling out the red carpet. A return to the long lost humanism of 'Don't Look Back In Anger', it's a reminder of Noel's knack of cheering up his audience just when they need it most." Q magazine held up the song as proof that "genius never completely left Oasis".
"Stop Crying Your Heart Out" was one of the songs played during the end credits of the movie, The Butterfly Effect, starring Ashton Kutcher and Amy Smart. It has been on the TV show Smallville too. The song also appeared after England's defeats in the 2002 Football World Cup and the 2006-07 Ashes. Noel Gallagher dedicated it to the English football team before playing it at the 2004 Glastonbury Festival. The song is also featured in the film Made of Honor, Starring Patrick Dempsey and Michelle Monaghan and appears towards the end of the film.
"10 Minutes of Noise and Confusion - Pt. Two" is the second part of a feature covering 48 hours on the road with Oasis during the Tour of Brotherly Love which took place in the USA with the Black Crowes during May and June 2001.