Durene, or 1,2,4,5-tetramethylbenzene, is an aromatic hydrocarbon used as a solvent. It is also an intermediate in the manufacture of pyromelletic acid, which is used for manufacturing curing agents, adhesives and coating materials. It is used in the manufacture of some raw materials for engineering plastics (polyimides) and cross-linking agent for alkyd resins.
1,2,4,5-Tetramethylbenzene has a simple proton NMR spectrum comprising two signals due to the 2 aromatic hydrogens (2H) and four methyl groups (12H). It is also readily soluble in chloroform. This compound is thus a useful internal standard.