Diosgenin

Diosgenin

[dahy-oz-jen-in, dahy-oz-juh-nin]
Diosgenin, a steroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted from the tubers of Dioscorea wild yam. The sugar-free, aglycone, diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and other steroid products.

Sources

It is present in Costus speciosus, Smilax menispermoidea, species of Paris, Trigonella, and Trillium, and many species of Dioscorea - D. althaeoides, colletti, futschauensis, gracillima, hispida, hypoglauca, mexicana nipponica, panthaica, parviflora, septemloba, and zingiberensis.

Clinical Uses

Diosgenin is the precursor for the semisynthesis of progesterone which in turn was used in early combined oral contraceptive pills. The unmodified steroid has estrogenic activity and can reduce the level of serum cholesterol.

References

External links

Search another word or see diosgeninon Dictionary | Thesaurus |Spanish
Copyright © 2014 Dictionary.com, LLC. All rights reserved.
  • Please Login or Sign Up to use the Recent Searches feature