Diethylcarbamazine (DEC) is an anthelmintic drug that does not resemble other antiparasitic compounds. It is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements.
In cases of onchocerciasis, another common filarial parasite, the drug is not used. This is because of the intense and unbearable itching associated with the dead subcutaneous parasites.
DEC continues to be the mainstay for treatment of patients with lymphatic filariasis and loiasis. DEC is also used in the prevention of dog heartworm Dirofilaria immitis.
Eisai Starts Free Supply of Diethylcarbamazine in Line with Its Global Commitment to Eliminate Lymphatic Filariasis
Nov 01, 2013; Eisai announced that it has begun the free supply of diethylcarbamazine citrate (DEC) 100 mg tablets produced at its Vizag...
Cost of mass annual single dose diethylcarbamazine distribution for the large scale control of lymphatic filariasis
Mar 01, 2000; Economic analysis of the revised strategy to control lymphatic filariasis with mass annual single dose diethylcarbamazine...