Dibutyl phthalate (DBP) is a commonly used plasticizer. It is also used as an additive to adhesives or printing inks. It is soluble in various organic solvents, e.g. in alcohol, ether and benzene.
DBP was added to the California Proposition 65 (1986) List of suspected teratogens in November 2006. It is a suspected endocrine disrupter. It was used in some nail polishes; all major producers began eliminating this chemical from nail polishes in the Fall of 2006.
Production of DBP by direct esterification of n-butanol
and phthalic anhydride
A study on CDC
data published in Environmental Health Perspectives
(EHP), revealed that American men with abdominal obesity
or insulin resistance
(a precursor to diabetes
) were more likely to have high levels of DEHP
metabolites in their urine than men without those problems.