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dextrose [dek-strohs]

dextrose

[dek-strohs]
dextrose: see glucose.
or dextrose or grape sugar or corn sugar

Organic compound, a simple sugar (monosaccharide), chemical formula C6H12O6. The product of photosynthesis in plants, it is found in fruits and honey. As the major circulating free sugar in blood, it is the source of energy in cell function and a major participant in metabolism. Control of its level and metabolism is of great importance (see insulin). Glucose and fructose make up sucrose. Glucose units in long chains make up polysaccharides (e.g., cellulose, glycogen, starch). Glucose is used in foods, medicine, brewing, and wine making and as the source of various other organic chemicals.

Learn more about glucose with a free trial on Britannica.com.

Acid Citrate Dextrose Solution (sometimes called Anticoagulant Citrate Dextrose Solution) is a solution of citric acid, sodium citrate and dextrose in water. It is mainly used as an anticoagulant to preserve blood, it is also used during procedures such as plasmapheresis instead of heparin. Two different solutions (Solution A and B) are defined by the United States Pharmacopeia.

They have the following properties:

Solution A (per 1000 mL)
Total Citrate (as Citric acid, anhydrous (C6H8O7)) 20.59 to 22.75g
Dextrose (C6H12O6*H2O) 23.28g to 25.73g
Sodium (Na) 4.90g to 5.42g

Solution B (per 1000 mL)
Total Citrate (as Citric acid, anhydrous (C6H8O7)) 12.37 to 13.67g
Dextrose (C6H12O6*H2O) 13.96 to 15.44g
Sodium (Na) 2.94 to 3.25g

To make use:

A B
Citric Acid, anhydrous (C6H8O7) 7.3g 4.4
Sodium Citrate, dihydrate 22.0g 13.2
Dextrose, monohydrate (C6H12O6*H2O) 24.5g 14.7
Water for Injection to make 1000 mL 1000 mL

Dissolve the ingredients and mix. Filter until clear.

References

United States Pharmacopeia 26, 2002, pp 158.

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