Mental illness characterized by the alternation of manic and depressive states. Depression is the more common symptom, and many patients experience only a brief period of overoptimism and mild euphoria during the manic phase. The condition, which seems to be inheritable, probably arises from malregulation of the amines norepinephrine, dopamine, and 5-hydroxytryptamine. It is most commonly treated with lithium carbonate.
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Depressive Symptoms in Epilepsy: Prevalence, Impact, Aetiology, Biological Correlates and Effect of Treatment with Antiepileptic Drugs
Jun 01, 2008; Abstract Occurring in up to 80% of patients with epilepsy, depression in epilepsy may manifest as (i) major depressive...