|Isomers of Cresol|
|Skeletal formula|| || || |
|Molar mass||108.14 g/mol|
| Appearance at room|
temperature and pressure
| greasy-looking solid |
ready to melt
on hot day
|thicker liquid||greasy-looking solid|
|mixture of cresols: [1319-77-3]|
|Density and phase||1.05 g/cm3, solid||1.03 g/cm3, liquid||1.02 g/cm3, liquid|
| Solubility in pure water|
|2.5 g/100 ml||2.4 g/100 ml||1.9 g/100 ml|
|soluble in strongly alkaline water|
|Melting point||29.8 °C (303.0 K)||11.8 °C (285.0 K)||35.5 °C (309.7 K)|
|Boiling point||191.0 °C (464.2 K)||202.0 °C (475.2 K)||201.9 °C (475.1 K)|
|Viscosity||solid at 25 °C||? cP at 25 °C||solid at 25 °C|
|Dipole moment||? D||? D||? D|
|Main hazards||flammable, ingestion and inhalation toxicity hazard|
|Flash point||81°C c.c.||86 °C||86 °C c.c.|
|R/S statement||R: 24/25-34 S: (1/2-)36/37/39-45|
|Supplementary data page|
|Structure & properties||n, εr, etc.|
|Thermodynamic data|| Phase behaviour|
Solid, liquid, gas
|Spectral data||UV, IR, NMR, MS|
|Related phenols||phenol, xylenols|
| Except where noted otherwise, data are given for|
materials in their standard state (at 25°C, 100 kPa)
Cresol solutions are used as household cleaners and disinfectants, perhaps most famously under the trade name Lysol. In the past, cresol solutions have been used as antiseptics in surgery, but they have been largely displaced in this role by less toxic compounds. Lysol was also advertised as a disinfecting vaginal douche in mid-twentieth century America.
Cresols are found in many foods and in wood and tobacco smoke, crude oil, coal tar, and in brown mixtures such as creosote, cresolene and cresylic acids, which are wood preservatives. Small organisms in soil and water produce cresols when they break down materials in the environment.
Xylenols are dimethylphenols, or they can be thought of as methylcresols.
Most exposures to cresols are at very low levels that are not harmful. When cresols are breathed, ingested, or applied to the skin at very high levels, they can be very harmful. Effects observed in people include irritation and burning of skin, eyes, mouth, and throat; abdominal pain and vomiting; heart damage; anemia; liver and kidney damage; facial paralysis; coma; and death.
Breathing high levels of cresols for a short time results in irritation of the nose and throat. Aside from these effects, very little is known about the effects of breathing cresols, for example, at lower levels over longer times.
Short-term and long-term studies with animals have shown similar effects from exposure to cresols. No human or animal studies have shown harmful effects from cresols on the ability to have children.
It is not known what the effects are from long-term ingestion or skin contact with low levels of cresols.
Gas Chromatographic-Mass Spectrometric Analysis for Measurement of p-Cresol and Its Conjugated Metabolites in Uremic and Normal Serum
Aug 01, 2005; p-cresol (4-methylphenol; 108 Da) is a protein-bound solute retained within the body in renal failure (1). p-cresol...