A "classic" ranging system used since the 1960s uses radar to time a radio signal's travel to a target (in this case, the rocket) and back. This technique is accurate to approximately 1%. The accuracy of this technique is limited by the need to create a sharp "pulse" of radio so that the start of the signal can be accurately defined. There are both practical and theoretical limits to the sharpness of the pulse. In addition, the timing of the signals often introduced inaccuracies of its own until the introduction of high precision clocks.
In MISTRAM, this was avoided by broadcasting a continuous signal. The basic system used a ground station located down range from the launch site (at Valkaria, Florida and Eleuthera Island, Bahamas) and a transponder on the vehicle. The tracking station transmitted an X-band carrier signal which the transponder responded to by re-broadcasting it on another (shifted) frequency. By slowly changing the frequency of the carrier broadcast from the station and comparing this with the phase of the signal being returned, ground control could measure the distance to the vehicle very accurately. Even with the analog circuitry used, MISTRAM was accurate to less than 1 km at the distance of the moon.
To meet more stringent ballistic missile test requirements, several systems were designed, procured and added to the US Air Force Eastern Range's instrumentation in the 1950s and 1960s. The AZUSA continuous wave tracking system was added to the Cape in the mid-1950s and Grand Bahama in the early 1960s. The AN/FPS-16 radar system was introduced at the Cape, Grand Bahama, San Salvador, Ascension and East Grand Bahama Island between 1958 and 1961. In the early 1960s, the MISTRAM (Missile Trajectory Measurement) system was installed at Valkaria, Florida and Eleuthera island in the Bahamas to support Minuteman missile flights.
MISTRAM is a sophisticated interferometer system consisting of a group of five receiving stations arranged in an L shape. Baselines are 10,000 ft. and 100,000 ft. The central stations contains a simple tracking antenna. The distance from the central station to the furthest remote station is approximately 100,000 ft. Antennas at the central station and the four remote stations follow the flight of a missile and receive signals from its radio beacon.
In the MISTRAM system, the ground station transmits a carrier to the spacecraft and the spacecraft returns this carrier on another frequency. The ground station sweeps the uplink carrier and the phase shift of the downlink carrier is measured (counted) while it is being swept. The round trip delay time can be shown to be T=(delta-phi)/(delta-f) ; where delta-f is the frequency shift (~4000 Hz for example) and delta-phi the measured phase shift in radians. Suppose T=2 sec (~lunar distance) then delta-phi=8000 radians, i.e. (8000*180)/Pi. Assume also that the phase can be measured with an accuracy of 1 deg, i.e. means that the range can be determined with a precision of (600000*1*Pi)/(2*8000*180)=0.33 km. An additional carrier quite near the one described above that remained fixed in frequency and used as a phase reference. That carrier and the two frequencies (that the sweep changed between) were generated as multiples of the same basic oscillator frequency. In this way, all signals would have a fixed phase relationship, as was done in MISTRAM. A similar technique was used in the Soviet Luna 20 spacecraft at 183.54 MHz to survey the moon's surface.
MISTRAM was a multistatic long baseline radar interferometer developed for precision measurements of missile trajectories at the US Air Force Eastern Test Range. Multistatic radar systems have a higher complexity with multiple transmitter and receiver subsystems employed in a coordinated manner at more than two sites. All of the geographically dispersed units contribute to the collective target acquisition, detection, position finding and resolution, with simultaneous reception at the receiver sites. In a simpler sense, multistatic radars are systems which have two or more receiving sites with a common spatial coverage area, and data from these coverage areas are combined and processed at a central location. These systems are considered to be multiple bistatic pairs. Multistatic radar systems have various uses, including prevention of jamming and anti-radar munitions.
Although this method of measurement is not new, either in theory or in practice, the unique manner in which the techniques were implemented in the MISTRAM system permit measurement of vehicle flight parameters with a degree of precision and accuracy not previously obtainable in other long baseline trajectory measurement systems. To a large extent, this was accomplished by a unique method of transferring intact the phase information in the signals from outlying stations to the central station. A two-way transmission path on each baseline was used to cancel out uncertainties due to variance in ground geometry and temperature. 
The transmitter at the master or central station generates two CW X-band frequencies, nominally 8148 MHz and 7884 to 7892 MHz. The higher frequency (the range signal) is very stable, whereas the lower frequency (the calibrated signal) is swept periodically over the indicated range. The airborne transponder receives the signals, amplifies & frequency shifts them by 68 MHz, and retransmits back to earth. The Doppler shift is used to determine velocity. 
The Florida MISTRAM system had 100,000 ft baselines (~18.9 mi.) with design performance as follows:
Range of Operation-
Velocity.............0 to 50,000 fps
Acceleration...........0 to 750 fps2
Elevation................5 to 85 deg
Range..................20 to 1000 mi
Measurement Uncertainties (RMS)-
Range Difference..............0.3 ft
Range Rate..................0.02 fps
Range Rate Difference......0.002 fps
(The last two quantities involve one-half second of smoothing.) 
The Transponder receives the two phase-coherent X-band cw signals transmitted from the ground equipment. A klystron with a 68 MHz coherent frequency offset is phase locked to each of the received signals. These klystrons provide the phase coherent return transmission. There are two separate phase locked loops, continuous and calibrate.
MISTRAM "A" Model Transponder Specifications
Operating Frequencies (Nominal)Continuous - 8148 MHz received :8216 MHz transmittedCalibrate - 7884 to 8992 (swept) received :7952 to 7960 (swept) transmitted
Input power - 5.25 amps maximum from 25.2 to 32.2 VDC Output power - 500 milliwatts min/channel Warmup time - 1 minute maximum at 0 degrees Celsius or above Acquisition Time - 0.1 second maximum Phase coherence - 256 MHz - within 45 degrees (0.25 foot range error max.)8 MHz - within 2 degrees (0.36 foot range error max.)Dynamic range = -39 to -105 dBm
Physical characteristicsSize: 8.9 x 12.4 x 5.4 inches (including mounting projections)Waveguide ports: Two reduced height X-band (1 Xmit; 1 Rcv)Life: 3 years. Operating 500 hours.
The debate in favor or against subsequent development of an M236-derived general purpose computer took more than one year and concluded finally with the victory of the M2360 project proponents in February 1963. The GE upper management was impressed by the opportunity to save the rental fees from IBM leased equipment used internally by GE (the cost of development of the new project was estimated to be offset by only one year of rentals). The other GE departments were not very impressed and were reluctant to jettison their IBM machines.
The GE-600 series was developed by a team led by John Couleur based on work done for the MISTRAM project in 1959. MISTRAM was a missile tracking system that was used on a number of projects (including Project Apollo) and the Air Force required a data-collection computer to be installed in a tracking station downrange from Cape Canaveral. The data would eventually be shared with the 36-bit IBM 7094 machine at the Cape, so the computer would likely have to be 36-bits as well (why they didn't use an IBM 7094 is something of a mystery). GE built a machine called the M236 for the task, and as a result of the 36-bit needs, it ended up acting a lot like the 7094.
The GE Heavy Military Electronics Department in Syracuse designed and built a tracking system for the ATLAS missile system named MISTRAM that was in fact an advanced computer system. This was quite in accordance with Cordiner’s directions since it would not develop a line of machines that be placed on the open market in competition with IBM. (Ralph J. Cordiner was Chairman & CEO of General Electric from 1958 to 1963.) This project also had the advantage that the up front development expenditures were to be paid by the U.S. government rather than GE, an arrangement much more satisfactory to GE's 570 “bean counters.” These circumstances brought about the possibility of duplicating the MISTRAM opportunity for the computer department. Much later, the result was an order for 32 computer department machines. However, the MISTRAM computer was the first in a line of developments by John Couleur that led to what may be regarded as the most successful and long-lasting machine - the GE 600 line. 
Subsequent development of improved tracking systems, UDOP and MISTRAM, at AFETR yielded much higher quality velocity tracking profiles. During the Minuteman II flight test program, significant improvements were made in the post-flight evaluation of the IMU accuracy. The most important of these improvement was the introduction of maximum likelihood error estimation using the Kalman algorithm to filter the velocity error profile. Continued improvement of the UDOP and MISTRAM tracking systems and refinement of the evaluation techniques during the Minuteman III flight test program made it possible to gain considerable insight into NS-20A1 IMU error sources.
In retrospect, Neelands said he did not get his greatest satisfaction from his work on the Atlas guidance (about which he said,"it was successful because of a bunch of other people who put it together and made it work"). It is MISTRAM, missile tracking and measuring system, that he remembers with greater pride. "Nothing could match it at the time for the complexity and precision it required," he recalls of the real-time measuring system for precisely tracking a missile's flight. One of his colleagues remembers, "In 1960 he solved the elusive problem of trajectory measurement -- of bringing together at one place for processing, the signals received from widely spaced receiving stations while overcoming inaccuracies due to the propagation anomalies in the medium connecting the stations. A related problem that Lew solved was how to do this using frequencies sufficiently high to develop the required angular measurement accuracy without measurement ambiuities and without requiring a large number of receiving stations to resolve these anbiguities." He conceived a system of unprecedented accuracy. The technical work on the Hermes A-3 rocket guidance was headed by Dr. Lewis J. Neelands and resulted in a successful system with the know-how later transferred to another ICBM guidance system known as the 8014 project and also to the highly accurate Mistram instrumentation equipment, all were based on use of a microwave interferometer.  Dr. Neelands passed away at his home in Gainesville Florida on July 17, 2007 at the age of 91.