Confluence is so named for the juncture of the Casselman River and Laurel Hill Creek with the Youghiogheny River. It therefore provides many opportunities for boating and fishing (and hiking, as Pennsylvania's highest point, Mount Davis, is located nearby).
According to the United States Census Bureau, the borough has a total area of 1.6 square miles (4.3 km²), of which, 1.6 square miles (4.1 km²) of it is land and 0.1 square miles (0.1 km²) of it (3.03%) is water. The borough is bordered to the south by the 2,840 acre Youghiogheny River Lake and to the north by the 19,052 acre Ohiopyle State Park.
There were 349 households out of which 25.8% had children under the age of 18 living with them, 48.4% were married couples living together, 9.2% had a female householder with no husband present, and 39.3% were non-families. 34.4% of all households were made up of individuals and 21.8% had someone living alone who was 65 years of age or older. The average household size was 2.26 and the average family size was 2.91.
In the borough the population was spread out with 20.3% under the age of 18, 7.0% from 18 to 24, 26.9% from 25 to 44, 22.7% from 45 to 64, and 23.3% who were 65 years of age or older. The median age was 42 years. For every 100 females there were 84.9 males. For every 100 females age 18 and over, there were 79.7 males.
The median income for a household in the borough was $23,462, and the median income for a family was $31,181. Males had a median income of $26,705 versus $19,750 for females. The per capita income for the borough was $12,129. About 15.0% of families and 21.2% of the population were below the poverty line, including 28.7% of those under age 18 and 20.4% of those age 65 or over.