In anatomy, the urethra (from Greek ουρήθρα - ourethra) is a tube which connects the urinary bladder to the outside of the body. The urethra has an excretory function in both sexes to pass urine to the outside, and also a reproductive function in the male, as a passage for semen.
The external urethral sphincter is a striated muscle that allows voluntary control over urination.
In the human male, the urethra is about 8 inches (15 cm) long and opens at the end of the penis. The inside of the urethra has a spiral groove (like rifling in a gun barrel), which makes the urine flow in a wide stream.
The urethra is divided into four parts in men, named after the location:
| Region | Description | Epithelium |
| pre-prostatic urethra | This is the intramural part of the urethra and varies between 0.5 and 1.5 cm in length depending the fullness of the bladder. | Transitional |
| prostatic urethra | Crosses through the prostate gland. There are several openings: (1) a small opening where sperm from the vas deferens and ejaculatory duct enters, (2) the prostatic ducts where fluid from the prostate enters, (3) an opening for the prostatic utricle, but nothing is added from it. These openings are collectively called the verumontanum. | Transitional |
| membranous urethra | A small (1 or 2 cm) portion passing through the external urethral sphincter. This is the narrowest part of the urethra. It is located in the deep perineal pouch. The ducts from the bulbourethral glands enter here. | Pseudostratified columnar |
| spongy urethra (or penile urethra) | Runs along the length of the penis on its ventral (underneath) surface. It is about 15-16 cm in length, and travels through the corpus spongiosum. The ducts from the urethral gland enter here. Some textbooks will subdivide the spongy urethra into two parts, the bulbous and pendulous urethra. | Pseudostratified columnar - proximally, Stratified squamous - distally |
The length of a male's urethra, and the fact it contains a number of bends, makes catheterisation more difficult.
There are small mucus-secreting urethral glands, that help protect the epithelium from the corrosive urine.
Endoscopy of the bladder via the urethra is called cystoscopy.