Wright-Patterson Air Force Base, U.S. military installation, 8,023 acres (3,247 hectares), W Ohio, NE of Dayton; est. 1917. One of the largest airport installations in the world, it is the air force's main research and development base, and the headquarters of the Air Force Logistics Command (national center for defense activities). The Aerospace Medical Laboratory and the Air Force Museum are also on the base.