D-threo-aldose 1-dehydrogenase

a D-threo-aldose + NAD⁺ $rightleftharpoons$ a D-threo-aldono-1,5-lactone + NADH + H⁺

Thus, the two substrates of this enzyme are D-threo-aldose and NAD⁺, whereas its 3 products are D-threo-aldono-1,5-lactone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-threo-aldose:NAD+ 1-oxidoreductase. Other names in common use include L-fucose dehydrogenase, (2S,3R)-aldose dehydrogenase, dehydrogenase, L-fucose, and L-fucose (D-arabinose) dehydrogenase. This enzyme participates in ascorbate and aldarate metabolism.

References

• Sasajima KI, Sinskey AJ "Oxidation of L-glucose by a Pseudomonad". Biochim. Biophys. Acta. 571 120–6.
• Schachter H, Sarney J, McGuire EJ, Roseman S "Isolation of diphosphopyridine nucleotide-dependent L-fucose dehydrogenase from pork liver". J. Biol. Chem. 244 4785–92.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes