Piccadilly, street of the City of Westminster borough, London, England. Starting at Piccadilly Circus (London's center of traffic and amusement), it runs to Hyde Park Corner. The street is lined with shops, hotels, and clubs. The Albany, a club, was the residence of T. B. Macaulay, W. E. Gladstone, Edward Bulwer-Lytton, and George Canning.